Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma
Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma
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Author / Creator
Nikolaev, Sergey I , Rimoldi, Donata , Iseli, Christian , Valsesia, Armand , Robyr, Daniel , Gehrig, Corinne , Harshman, Keith , Guipponi, Michel , Bukach, Olesya , Zoete, Vincent , Michielin, Olivier , Muehlethaler, Katja , Speiser, Daniel , Beckmann, Jacques S , Xenarios, Ioannis , Halazonetis, Thanos D , Jongeneel, C Victor , Stevenson, Brian J and Antonarakis, Stylianos E
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Sergey Nikolaev, Stylianos Antonarakis and colleagues report exome sequencing of seven melanoma cell lines and matched germline cells. They identify recurring somatic mutations in
MAP2K1
and
MAP2K2
occurring at an overall frequency of 8%.
We performed exome sequencing to detect somatic mutations in protein-coding regions in seven mel...
Alternative Titles
Full title
Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma
Authors, Artists and Contributors
Author / Creator
Rimoldi, Donata
Iseli, Christian
Valsesia, Armand
Robyr, Daniel
Gehrig, Corinne
Harshman, Keith
Guipponi, Michel
Bukach, Olesya
Zoete, Vincent
Michielin, Olivier
Muehlethaler, Katja
Speiser, Daniel
Beckmann, Jacques S
Xenarios, Ioannis
Halazonetis, Thanos D
Jongeneel, C Victor
Stevenson, Brian J
Antonarakis, Stylianos E
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1034820777
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1034820777
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.1026
