Introduction of silent mutations into the NP gene of influenza A viruses as a possible strategy for...
Introduction of silent mutations into the NP gene of influenza A viruses as a possible strategy for the creation of a live attenuated vaccine
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Publisher
Netherlands: Elsevier Ltd
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Language
English
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Publisher
Netherlands: Elsevier Ltd
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Scope and Contents
Contents
Highlights ► Influenza A virus replication was impaired by silent mutations in the NP gene. ► Influenza A virus containing silently mutated NP gene was attenuated in mice. ► This may represent a novel strategy for development of live attenuated vaccine.
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Full title
Introduction of silent mutations into the NP gene of influenza A viruses as a possible strategy for the creation of a live attenuated vaccine
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TN_cdi_proquest_miscellaneous_1034825090
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1034825090
Other Identifiers
ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2012.04.070
