Blockade of CD70-CD27 interaction inhibits induction of allergic lung inflammation in mice
Blockade of CD70-CD27 interaction inhibits induction of allergic lung inflammation in mice
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Publisher
United States: American Thoracic Society
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Language
English
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Publisher
United States: American Thoracic Society
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Contents
The interaction between the TNF receptor family member CD27 and its ligand CD70 provides a costimulatory signal for T-cell activation. In this study, we investigated the effects of neutralizing anti-CD70 monoclonal antibody (mAb) in a murine model of allergic lung inflammation to determine whether CD27 contributes to the development of pathogenic T...
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Full title
Blockade of CD70-CD27 interaction inhibits induction of allergic lung inflammation in mice
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TN_cdi_proquest_miscellaneous_1037884656
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1037884656
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ISSN
1044-1549
E-ISSN
1535-4989
DOI
10.1165/rcmb.2011-0354OC