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Blockade of CD70-CD27 interaction inhibits induction of allergic lung inflammation in mice

Blockade of CD70-CD27 interaction inhibits induction of allergic lung inflammation in mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1037884656

Blockade of CD70-CD27 interaction inhibits induction of allergic lung inflammation in mice

About this item

Full title

Blockade of CD70-CD27 interaction inhibits induction of allergic lung inflammation in mice

Publisher

United States: American Thoracic Society

Journal title

American journal of respiratory cell and molecular biology, 2012-09, Vol.47 (3), p.298-305

Language

English

Formats

Publication information

Publisher

United States: American Thoracic Society

More information

Scope and Contents

Contents

The interaction between the TNF receptor family member CD27 and its ligand CD70 provides a costimulatory signal for T-cell activation. In this study, we investigated the effects of neutralizing anti-CD70 monoclonal antibody (mAb) in a murine model of allergic lung inflammation to determine whether CD27 contributes to the development of pathogenic T...

Alternative Titles

Full title

Blockade of CD70-CD27 interaction inhibits induction of allergic lung inflammation in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1037884656

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1037884656

Other Identifiers

ISSN

1044-1549

E-ISSN

1535-4989

DOI

10.1165/rcmb.2011-0354OC

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