Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel a...
Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON–TIMI 38 trial: a pharmacogenetic analysis
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Kidlington: Elsevier Ltd
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English
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Kidlington: Elsevier Ltd
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Summary Background Clopidogrel and prasugrel are subject to efflux via P-glycoprotein (encoded by ABCB1 , also known as MDR1 ). ABCB1 polymorphisms, particularly 3435C→T, may affect drug transport and efficacy. We aimed to assess the effect of this polymorphism by itself and alongside variants in CYP2C19 on cardiovascular outcomes in patients treat...
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Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON–TIMI 38 trial: a pharmacogenetic analysis
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TN_cdi_proquest_miscellaneous_1038595294
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1038595294
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ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(10)61273-1
