High abundance of plasma cells secreting transglutaminase 2–specific IgA autoantibodies with limited...
High abundance of plasma cells secreting transglutaminase 2–specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
IgA antibodies directed against tissue transglutaminase 2 (TG2) are used as a serological marker of celiac disease. Ludvig M. Sollid and his colleagues provide an unbiased and thorough characterization of the mucosal antibody response directly from the effector compartment. They report that TG2-specific plasma cells are expanded in the duodenal muc...
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High abundance of plasma cells secreting transglutaminase 2–specific IgA autoantibodies with limited somatic hypermutation in celiac disease intestinal lesions
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TN_cdi_proquest_miscellaneous_1038601563
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1038601563
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.2656
