OX40 signaling favors the induction of T(H)9 cells and airway inflammation
OX40 signaling favors the induction of T(H)9 cells and airway inflammation
About this item
Full title
OX40 signaling favors the induction of T(H)9 cells and airway inflammation
Author / Creator
Publisher
United States
Journal title
Nature immunology, 2012-10, Vol.13 (10), p.981-990
Language
English
Formats
Publication information
Publisher
United States
Subjects
More information
Scope and Contents
Contents
The mechanisms that regulate the T(H)9 subset of helper T cells and diseases mediated by T(H)9 cells remain poorly defined. Here we found that the costimulatory receptor OX40 was a powerful inducer of T(H)9 cells in vitro and T(H)9 cell-dependent airway inflammation in vivo. In polarizing conditions based on transforming growth factor-β (TGF-β), li...
Alternative Titles
Full title
OX40 signaling favors the induction of T(H)9 cells and airway inflammation
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Record Identifier
TN_cdi_proquest_miscellaneous_1069208465
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1069208465
Other Identifiers
E-ISSN
1529-2916
DOI
10.1038/ni.2390
