Global identification of MLL2-targeted loci reveals MLL2’s role in diverse signaling pathways
Global identification of MLL2-targeted loci reveals MLL2’s role in diverse signaling pathways
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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Myeloid/lymphoid or mixed-lineage leukemia (MLL)-family genes encode histone lysine methyltransferases that play important roles in epigenetic regulation of gene transcription. MLL genes are frequently mutated in human cancers. Unlike MLL1, MLL2 (also known as ALR/MLL4) and its homolog MLL3 are not well-understood. Specifically, little is known reg...
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Global identification of MLL2-targeted loci reveals MLL2’s role in diverse signaling pathways
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TN_cdi_proquest_miscellaneous_1115063191
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1115063191
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1208807109