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Global identification of MLL2-targeted loci reveals MLL2’s role in diverse signaling pathways

Global identification of MLL2-targeted loci reveals MLL2’s role in diverse signaling pathways

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1115063191

Global identification of MLL2-targeted loci reveals MLL2’s role in diverse signaling pathways

About this item

Full title

Global identification of MLL2-targeted loci reveals MLL2’s role in diverse signaling pathways

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (43), p.17603-17608

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Myeloid/lymphoid or mixed-lineage leukemia (MLL)-family genes encode histone lysine methyltransferases that play important roles in epigenetic regulation of gene transcription. MLL genes are frequently mutated in human cancers. Unlike MLL1, MLL2 (also known as ALR/MLL4) and its homolog MLL3 are not well-understood. Specifically, little is known reg...

Alternative Titles

Full title

Global identification of MLL2-targeted loci reveals MLL2’s role in diverse signaling pathways

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1115063191

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1115063191

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1208807109

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