Manipulating nucleosome disfavoring sequences allows fine-tune regulation of gene expression in yeas...
Manipulating nucleosome disfavoring sequences allows fine-tune regulation of gene expression in yeast
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Eran Segal and colleagues measure the promoter activities of 70 different constructed promoter variants and find that poly(dA:dT) tracts significantly affect transcriptional outcome. They suggest that this is mediated by altering nucleosome organization and that these sequences can be manipulated to fine tune regulation of gene expression.
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Full title
Manipulating nucleosome disfavoring sequences allows fine-tune regulation of gene expression in yeast
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TN_cdi_proquest_miscellaneous_1125228932
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1125228932
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.2305
