From Clinical Observation to Mechanism — Heyde's Syndrome
From Clinical Observation to Mechanism — Heyde's Syndrome
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Publisher
Waltham, MA: Massachusetts Medical Society
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Language
English
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Publisher
Waltham, MA: Massachusetts Medical Society
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Contents
In 1958, E.C. Heyde noted an association between aortic-valve stenosis and GI bleeding, which led to identification of the mechanism of the bleeding: fragmentation of high-molecular-weight multimers of von Willebrand factor on the stenotic valve led to acquired von Willebrand's disease.
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Clinical Implications of Basic Research
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Full title
From Clinical Observation to Mechanism — Heyde's Syndrome
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TN_cdi_proquest_miscellaneous_1171861348
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1171861348
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMcibr1205363
