Robust 4C-seq data analysis to screen for regulatory DNA interactions
Robust 4C-seq data analysis to screen for regulatory DNA interactions
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
A high-resolution 4C-seq protocol involving two restriction digests and a revised analysis pipeline allows robust detection of physical interactions between regulatory DNA elements.
Regulatory DNA elements can control the expression of distant genes via physical interactions. Here we present a cost-effective methodology and computational analysi...
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Full title
Robust 4C-seq data analysis to screen for regulatory DNA interactions
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TN_cdi_proquest_miscellaneous_1171871465
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1171871465
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ISSN
1548-7091
E-ISSN
1548-7105
DOI
10.1038/nmeth.2173