The recombinant tuberculosis vaccine rBCG Δ ureC::hly + induces apoptotic vesicles for improved prim...
The recombinant tuberculosis vaccine rBCG Δ ureC::hly + induces apoptotic vesicles for improved priming of CD4+ and CD8+ T cells
About this item
Full title
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Publisher
Netherlands: Elsevier Ltd
Journal title
Language
English
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Publisher
Netherlands: Elsevier Ltd
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Scope and Contents
Contents
Highlights ► Macrophages infected with recombinant (r) BCG become apoptotic. ► Apoptotic vesicles contain antigenic cargo. ► Engulfment of apoptotic vesicles by dendritic cells results in crosspriming. ► Crosspriming leads to better T cell stimulation. ► Superior protection by rBCG involves crosspriming.
Alternative Titles
Full title
The recombinant tuberculosis vaccine rBCG Δ ureC::hly + induces apoptotic vesicles for improved priming of CD4+ and CD8+ T cells
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TN_cdi_proquest_miscellaneous_1221853911
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1221853911
Other Identifiers
ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2012.10.031
