Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub
Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Antigen receptor locus V(D)J recombination requires interactions between widely separated variable (V), diversity (D), and joining (J) gene segments, but the mechanisms that generate these interactions are not well understood. Here we assessed mechanisms that direct developmental stage-specific long-distance interactions at the Tcra/Tcrd locus. The...
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Full title
Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub
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TN_cdi_proquest_miscellaneous_1239054726
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1239054726
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1214131109
