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c-Jun N-terminal kinase has a pivotal role in the maintenance of self-renewal and tumorigenicity in...

c-Jun N-terminal kinase has a pivotal role in the maintenance of self-renewal and tumorigenicity in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1257732775

c-Jun N-terminal kinase has a pivotal role in the maintenance of self-renewal and tumorigenicity in glioma stem-like cells

About this item

Full title

c-Jun N-terminal kinase has a pivotal role in the maintenance of self-renewal and tumorigenicity in glioma stem-like cells

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2012-11, Vol.31 (44), p.4655-4666

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Uncovering the mechanisms that govern the maintenance of stem-like cancer cells is critical for developing therapeutic strategies for targeting these cells. Constitutive activation of c-Jun N-terminal kinase (JNK) has been reported in gliomas and correlates with histological grade. Here, we found that JNK signaling is crucial for the maintenance of...

Alternative Titles

Full title

c-Jun N-terminal kinase has a pivotal role in the maintenance of self-renewal and tumorigenicity in glioma stem-like cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1257732775

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1257732775

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/onc.2011.634

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