UHRF1 coordinates peroxisome proliferator activated receptor gamma (PPARG) epigenetic silencing and...
UHRF1 coordinates peroxisome proliferator activated receptor gamma (PPARG) epigenetic silencing and mediates colorectal cancer progression
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Author / Creator
Sabatino, L , Fucci, A , Pancione, M , Carafa, V , Nebbioso, A , Pistore, C , Babbio, F , Votino, C , Laudanna, C , Ceccarelli, M , Altucci, L , Bonapace, I M and Colantuoni, V
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Peroxisome proliferator-activated receptor gamma (
PPARG
) inactivation has been identified as an important step in colorectal cancer (CRC) progression, although the events involved have been partially clarified. UHRF1 is emerging as a cofactor that coordinates the epigenetic silencing of tumor suppressor genes, but its role in CRC remains el...
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Full title
UHRF1 coordinates peroxisome proliferator activated receptor gamma (PPARG) epigenetic silencing and mediates colorectal cancer progression
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TN_cdi_proquest_miscellaneous_1257778797
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1257778797
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2012.3