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UHRF1 coordinates peroxisome proliferator activated receptor gamma (PPARG) epigenetic silencing and...

UHRF1 coordinates peroxisome proliferator activated receptor gamma (PPARG) epigenetic silencing and...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1257778797

UHRF1 coordinates peroxisome proliferator activated receptor gamma (PPARG) epigenetic silencing and mediates colorectal cancer progression

About this item

Full title

UHRF1 coordinates peroxisome proliferator activated receptor gamma (PPARG) epigenetic silencing and mediates colorectal cancer progression

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2012-12, Vol.31 (49), p.5061-5072

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Peroxisome proliferator-activated receptor gamma (
PPARG
) inactivation has been identified as an important step in colorectal cancer (CRC) progression, although the events involved have been partially clarified. UHRF1 is emerging as a cofactor that coordinates the epigenetic silencing of tumor suppressor genes, but its role in CRC remains el...

Alternative Titles

Full title

UHRF1 coordinates peroxisome proliferator activated receptor gamma (PPARG) epigenetic silencing and mediates colorectal cancer progression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1257778797

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1257778797

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/onc.2012.3

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