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SNP-based mapping arrays reveal high genomic complexity in monoclonal gammopathies, from MGUS to mye...

SNP-based mapping arrays reveal high genomic complexity in monoclonal gammopathies, from MGUS to mye...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1257792181

SNP-based mapping arrays reveal high genomic complexity in monoclonal gammopathies, from MGUS to myeloma status

About this item

Full title

SNP-based mapping arrays reveal high genomic complexity in monoclonal gammopathies, from MGUS to myeloma status

Publisher

London: Nature Publishing Group UK

Journal title

Leukemia, 2012-12, Vol.26 (12), p.2521-2529

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Genetic events mediating transformation from premalignant monoclonal gammopathies (MG) to multiple myeloma (MM) are unknown. To obtain a comprehensive genomic profile of MG from the early to late stages, we performed high-resolution analysis of purified plasma cells from 20 MGUS, 20 smoldering MM (SMM) and 34 MM by high-density 6.0 SNP array. A pro...

Alternative Titles

Full title

SNP-based mapping arrays reveal high genomic complexity in monoclonal gammopathies, from MGUS to myeloma status

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1257792181

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1257792181

Other Identifiers

ISSN

0887-6924

E-ISSN

1476-5551

DOI

10.1038/leu.2012.128

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