Impact of NOTCH1/FBXW7 mutations on outcome in pediatric T-cell acute lymphoblastic leukemia patient...
Impact of NOTCH1/FBXW7 mutations on outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on the MRC UKALL 2003 trial
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Author / Creator
Jenkinson, S , Koo, K , Mansour, M R , Goulden, N , Vora, A , Mitchell, C , Wade, R , Richards, S , Hancock, J , Moorman, A V , Linch, D C and Gale, R E
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Activating mutations in the
NOTCH1
pathway are frequent in pediatric T-cell acute lymphoblastic leukemia (T-ALL) but their role in refining risk stratification is unclear. We screened 162 pediatric T-ALL patients treated on the MRC UKALL2003 trial for
NOTCH1/FBXW7
gene mutations and related genotype to response to therapy and long-term...
Alternative Titles
Full title
Impact of NOTCH1/FBXW7 mutations on outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on the MRC UKALL 2003 trial
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Record Identifier
TN_cdi_proquest_miscellaneous_1273350153
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1273350153
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2012.176