SIRT1 suppresses PMA and ionomycin-induced ICAM-1 expression in endothelial cells
SIRT1 suppresses PMA and ionomycin-induced ICAM-1 expression in endothelial cells
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Author / Creator
Jia, YuYan , Gao, Peng , Chen, HouZao , Wan, YanZhen , Zhang, Ran , Zhang, ZhuQin , Yang, RuiFeng , Wang, Xu , Xu, Jing and Liu, DePei
Publisher
Beijing: Science China Press
Journal title
Language
English
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Publisher
Beijing: Science China Press
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Scope and Contents
Contents
Intercellular adhesion molecule-1 (ICAM-1) plays an important role in the recruitment of leukocytes to the endothelium, which causes inflammation and initiation of atherosclerosis. We have previously shown that endothelium-specific over-expression of class III deacetylase SIRT1 decreases atherosclerosis. We therefore addressed the hypothesis that S...
Alternative Titles
Full title
SIRT1 suppresses PMA and ionomycin-induced ICAM-1 expression in endothelial cells
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Record Identifier
TN_cdi_proquest_miscellaneous_1273513879
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1273513879
Other Identifiers
ISSN
1674-7305
E-ISSN
1869-1889
DOI
10.1007/s11427-012-4407-7