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SIRT1 suppresses PMA and ionomycin-induced ICAM-1 expression in endothelial cells

SIRT1 suppresses PMA and ionomycin-induced ICAM-1 expression in endothelial cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1273513879

SIRT1 suppresses PMA and ionomycin-induced ICAM-1 expression in endothelial cells

About this item

Full title

SIRT1 suppresses PMA and ionomycin-induced ICAM-1 expression in endothelial cells

Publisher

Beijing: Science China Press

Journal title

Science China. Life sciences, 2013, Vol.56 (1), p.19-25

Language

English

Formats

Publication information

Publisher

Beijing: Science China Press

More information

Scope and Contents

Contents

Intercellular adhesion molecule-1 (ICAM-1) plays an important role in the recruitment of leukocytes to the endothelium, which causes inflammation and initiation of atherosclerosis. We have previously shown that endothelium-specific over-expression of class III deacetylase SIRT1 decreases atherosclerosis. We therefore addressed the hypothesis that S...

Alternative Titles

Full title

SIRT1 suppresses PMA and ionomycin-induced ICAM-1 expression in endothelial cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1273513879

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1273513879

Other Identifiers

ISSN

1674-7305

E-ISSN

1869-1889

DOI

10.1007/s11427-012-4407-7

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