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IL-4 Inhibits the Melanogenesis of Normal Human Melanocytes through the JAK2–STAT6 Signaling Pathway

IL-4 Inhibits the Melanogenesis of Normal Human Melanocytes through the JAK2–STAT6 Signaling Pathway

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1273543368

IL-4 Inhibits the Melanogenesis of Normal Human Melanocytes through the JAK2–STAT6 Signaling Pathway

About this item

Full title

IL-4 Inhibits the Melanogenesis of Normal Human Melanocytes through the JAK2–STAT6 Signaling Pathway

Publisher

United States: Elsevier Inc

Journal title

Journal of investigative dermatology, 2013-02, Vol.133 (2), p.528-536

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

Skin diseases can be characterized by their predominant CD4-positive T-helper (Th) cell profiles. Chronic dermatological conditions often give rise to abnormal skin pigmentation. To understand the role of Th cells in pigmentation, the effects of the major Th cell cytokines, IFNγ, IL-4, and IL-17A, on melanogenesis were evaluated using cultured norm...

Alternative Titles

Full title

IL-4 Inhibits the Melanogenesis of Normal Human Melanocytes through the JAK2–STAT6 Signaling Pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1273543368

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1273543368

Other Identifiers

ISSN

0022-202X

E-ISSN

1523-1747

DOI

10.1038/jid.2012.331

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