Spironolactone prevents chronic kidney disease caused by ischemic acute kidney injury
Spironolactone prevents chronic kidney disease caused by ischemic acute kidney injury
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Publisher
United States: Elsevier Inc
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Language
English
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Publisher
United States: Elsevier Inc
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Contents
Acute kidney injury (AKI) has been recognized as a risk factor for the development of chronic kidney disease (CKD). Aldosterone has a critical role in promoting renal injury induced by ischemia. Here, we evaluated whether spironolactone administered before or after AKI caused by ischemia protects against CKD. In the first set of experiments, Wistar...
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Full title
Spironolactone prevents chronic kidney disease caused by ischemic acute kidney injury
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TN_cdi_proquest_miscellaneous_1273707143
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1273707143
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ISSN
0085-2538
E-ISSN
1523-1755
DOI
10.1038/ki.2012.352