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Spironolactone prevents chronic kidney disease caused by ischemic acute kidney injury

Spironolactone prevents chronic kidney disease caused by ischemic acute kidney injury

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1273707143

Spironolactone prevents chronic kidney disease caused by ischemic acute kidney injury

About this item

Full title

Spironolactone prevents chronic kidney disease caused by ischemic acute kidney injury

Publisher

United States: Elsevier Inc

Journal title

Kidney international, 2013-01, Vol.83 (1), p.93-103

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

Acute kidney injury (AKI) has been recognized as a risk factor for the development of chronic kidney disease (CKD). Aldosterone has a critical role in promoting renal injury induced by ischemia. Here, we evaluated whether spironolactone administered before or after AKI caused by ischemia protects against CKD. In the first set of experiments, Wistar...

Alternative Titles

Full title

Spironolactone prevents chronic kidney disease caused by ischemic acute kidney injury

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1273707143

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1273707143

Other Identifiers

ISSN

0085-2538

E-ISSN

1523-1755

DOI

10.1038/ki.2012.352

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