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Growth arrest–specific protein 1 is a novel endogenous inhibitor of glomerular cell activation and p...

Growth arrest–specific protein 1 is a novel endogenous inhibitor of glomerular cell activation and p...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1283731882

Growth arrest–specific protein 1 is a novel endogenous inhibitor of glomerular cell activation and proliferation

About this item

Full title

Growth arrest–specific protein 1 is a novel endogenous inhibitor of glomerular cell activation and proliferation

Publisher

United States: Elsevier Inc

Journal title

Kidney international, 2013-02, Vol.83 (2), p.251-263

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

Growth arrest–specific protein-1 (GAS1) is a GPI-anchored protein which is highly expressed in embryonic mouse fibroblasts and inhibits their proliferation. Glomerular mesangial cells release soluble GAS1 protein into the supernatant in vitro. Growth arrest led to GAS1 overexpression and increased release. Secretion involved disintegrin and metallo...

Alternative Titles

Full title

Growth arrest–specific protein 1 is a novel endogenous inhibitor of glomerular cell activation and proliferation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1283731882

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1283731882

Other Identifiers

ISSN

0085-2538

E-ISSN

1523-1755

DOI

10.1038/ki.2012.400

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