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Enhancement of social novelty discrimination by positive allosteric modulators at metabotropic gluta...

Enhancement of social novelty discrimination by positive allosteric modulators at metabotropic gluta...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1291603382

Enhancement of social novelty discrimination by positive allosteric modulators at metabotropic glutamate 5 receptors: adolescent administration prevents adult-onset deficits induced by neonatal treatment with phencyclidine

About this item

Full title

Enhancement of social novelty discrimination by positive allosteric modulators at metabotropic glutamate 5 receptors: adolescent administration prevents adult-onset deficits induced by neonatal treatment with phencyclidine

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Psychopharmacology, 2013-02, Vol.225 (3), p.579-594

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

Metabotropic glutamate-5 receptors (mGluR5), which physically and functionally interact with
N
-methyl-
d
-Aspartate (NMDA) receptors, likewise control cognitive processes and have been proposed as targets for novel classes of antipsychotic agent. Since social cognition is impaired in schizophrenia and disrupted by NMDA receptor antagon...

Alternative Titles

Full title

Enhancement of social novelty discrimination by positive allosteric modulators at metabotropic glutamate 5 receptors: adolescent administration prevents adult-onset deficits induced by neonatal treatment with phencyclidine

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1291603382

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1291603382

Other Identifiers

ISSN

0033-3158

E-ISSN

1432-2072

DOI

10.1007/s00213-012-2845-3

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