Performance of High Quality Minicircle DNA for In Vitro and In Vivo Gene Transfer
Performance of High Quality Minicircle DNA for In Vitro and In Vivo Gene Transfer
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Publisher
New York: Springer-Verlag
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Language
English
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Publisher
New York: Springer-Verlag
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Scope and Contents
Contents
Plasmid DNA is frequently used particularly for nonviral gene therapy. Conventional plasmid DNA contains bacterial backbone and resistance gene sequences, as well as immunogenic CpG motifs. These components are not required for transgene expression. They represent a potential risk for safe clinical application and reduce gene transfer rates as well...
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Full title
Performance of High Quality Minicircle DNA for In Vitro and In Vivo Gene Transfer
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TN_cdi_proquest_miscellaneous_1291610212
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1291610212
Other Identifiers
ISSN
1073-6085
E-ISSN
1559-0305
DOI
10.1007/s12033-012-9535-6
