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STING and the innate immune response to nucleic acids in the cytosol

STING and the innate immune response to nucleic acids in the cytosol

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1291620478

STING and the innate immune response to nucleic acids in the cytosol

About this item

Full title

STING and the innate immune response to nucleic acids in the cytosol

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2013-01, Vol.14 (1), p.19-26

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Cytosolic detection of pathogen-derived nucleic acids is critical for the initiation of innate immune defense against diverse bacterial, viral and eukaryotic pathogens. Conversely, inappropriate responses to cytosolic nucleic acids can produce severe autoimmune pathology. The host protein STING has been identified as a central signaling molecule in...

Alternative Titles

Full title

STING and the innate immune response to nucleic acids in the cytosol

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1291620478

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1291620478

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.2491

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