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The histone deacetylase, SIRT1, contributes to the resistance of young mice to ischemia/reperfusion-...

The histone deacetylase, SIRT1, contributes to the resistance of young mice to ischemia/reperfusion-...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1314338494

The histone deacetylase, SIRT1, contributes to the resistance of young mice to ischemia/reperfusion-induced acute kidney injury

About this item

Full title

The histone deacetylase, SIRT1, contributes to the resistance of young mice to ischemia/reperfusion-induced acute kidney injury

Publisher

United States: Elsevier Inc

Journal title

Kidney international, 2013-03, Vol.83 (3), p.404-413

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

Acute kidney injury (AKI) is a critical condition with a mortality rate as high as 50% and significantly contributes to the burden of end-stage renal disease (ESRD) requiring renal replacement therapy. The incidence and prognosis of AKI have been shown to vary with patient age, with younger individuals being more resistant to AKI. In mice, clamping...

Alternative Titles

Full title

The histone deacetylase, SIRT1, contributes to the resistance of young mice to ischemia/reperfusion-induced acute kidney injury

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1314338494

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1314338494

Other Identifiers

ISSN

0085-2538

E-ISSN

1523-1755

DOI

10.1038/ki.2012.394

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