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Production of Serotonin by Tryptophan Hydroxylase 1 and Release via Platelets Contribute to Allergic...

Production of Serotonin by Tryptophan Hydroxylase 1 and Release via Platelets Contribute to Allergic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1314709517

Production of Serotonin by Tryptophan Hydroxylase 1 and Release via Platelets Contribute to Allergic Airway Inflammation

About this item

Full title

Production of Serotonin by Tryptophan Hydroxylase 1 and Release via Platelets Contribute to Allergic Airway Inflammation

Publisher

New York, NY: American Thoracic Society

Journal title

American journal of respiratory and critical care medicine, 2013-03, Vol.187 (5), p.476-485

Language

English

Formats

Publication information

Publisher

New York, NY: American Thoracic Society

More information

Scope and Contents

Contents

5-Hydroxytryptamine (5-HT) is involved in the pathogenesis of allergic airway inflammation (AAI). It is unclear, however, how 5-HT contributes to AAI and whether this depends on tryptophan hydroxylase (TPH) 1, the critical enzyme for peripheral 5-HT synthesis.
To elucidate the role of TPH1 and the peripheral source of 5-HT in asthma pathogenesis...

Alternative Titles

Full title

Production of Serotonin by Tryptophan Hydroxylase 1 and Release via Platelets Contribute to Allergic Airway Inflammation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1314709517

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1314709517

Other Identifiers

ISSN

1073-449X

E-ISSN

1535-4970

DOI

10.1164/rccm.201208-1440OC

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