Integration of the accelerator Aha1 in the Hsp90 co-chaperone cycle
Integration of the accelerator Aha1 in the Hsp90 co-chaperone cycle
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
The role of co-chaperone and Hsp90 activator Aha1 is now examined in conjunction with other co-chaperones
in vivo
and
in vitro
, to reveal how they regulate the progression of the Hsp90 cycle. Aha1 and Cpr6 interact with and activate Hsp90 in a synergistic manner and displace the inhibitory co-chaperone Sti1. Aha1 is eventually released...
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Full title
Integration of the accelerator Aha1 in the Hsp90 co-chaperone cycle
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TN_cdi_proquest_miscellaneous_1315134070
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1315134070
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ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.2502