DNA vaccine encoding CD40 targeted to dendritic cells in situ prevents the development of Heymann ne...
DNA vaccine encoding CD40 targeted to dendritic cells in situ prevents the development of Heymann nephritis in rats
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Publisher
United States: Elsevier Inc
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Language
English
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Publisher
United States: Elsevier Inc
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Scope and Contents
Contents
The CD40-CD154 costimulatory pathway has been shown to be critical for both T- and B-cell activation in autoimmune disease. Here, we assessed the effects of blocking this pathway using CD40 DNA vaccine enhanced by dendritic cell targeting on the development of active Heymann nephritis, a rat model of human membranous nephropathy. DNA vaccination de...
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Full title
DNA vaccine encoding CD40 targeted to dendritic cells in situ prevents the development of Heymann nephritis in rats
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TN_cdi_proquest_miscellaneous_1315613781
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1315613781
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ISSN
0085-2538
E-ISSN
1523-1755
DOI
10.1038/ki.2012.374
