Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and di...
Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The balance between self-renewal and differentiation of adult stem cells is essential for tissue homeostasis. Here we show that in the haematopoietic system this process is governed by polycomb chromobox (Cbx) proteins. Cbx7 is specifically expressed in haematopoietic stem cells (HSCs), and its overexpression enhances self-renewal and induces leuka...
Alternative Titles
Full title
Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1323796461
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1323796461
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb2701
