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Nicotine/cigarette smoke promotes metastasis of pancreatic cancer through alpha 7nAChR-mediated MUC4...

Nicotine/cigarette smoke promotes metastasis of pancreatic cancer through alpha 7nAChR-mediated MUC4...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1323812003

Nicotine/cigarette smoke promotes metastasis of pancreatic cancer through alpha 7nAChR-mediated MUC4 upregulation

About this item

Full title

Nicotine/cigarette smoke promotes metastasis of pancreatic cancer through alpha 7nAChR-mediated MUC4 upregulation

Journal title

Oncogene, 2013-03, Vol.32 (11), p.1384-1395

Language

English

Formats

More information

Scope and Contents

Contents

Despite evidence that long-term smoking is the leading risk factor for pancreatic malignancies, the underlying mechanism(s) for cigarette-smoke (CS)-induced pancreatic cancer (PC) pathogenesis has not been well established. Our previous studies revealed an aberrant expression of the MUC4 mucin in PC as compared with the normal pancreas, and its ass...

Alternative Titles

Full title

Nicotine/cigarette smoke promotes metastasis of pancreatic cancer through alpha 7nAChR-mediated MUC4 upregulation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1323812003

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1323812003

Other Identifiers

ISSN

0950-9232

DOI

10.1038/onc.2012.163

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