OASL1 inhibits translation of the type I interferon–regulating transcription factor IRF7
OASL1 inhibits translation of the type I interferon–regulating transcription factor IRF7
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New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
The production of type I interferon is regulated by the master transcription factor IRF7. Kim and colleagues show that OASL1 specifically recognizes IRF7 mRNA and inhibits its translation and the production of type I interferon.
The production of type I interferon is essential for viral clearance but is kept under tight control to avoid unnecess...
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Full title
OASL1 inhibits translation of the type I interferon–regulating transcription factor IRF7
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TN_cdi_proquest_miscellaneous_1323812952
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1323812952
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.2535
