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The Hippo pathway and human cancer

The Hippo pathway and human cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1328515214

The Hippo pathway and human cancer

About this item

Full title

The Hippo pathway and human cancer

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Cancer, 2013-04, Vol.13 (4), p.246-257

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
The Hippo pathway is an evolutionarily conserved regulator of tissue growth.
The Hippo pathway controls multiple cellular functions that are central to tumorigenesis, including proliferation and apoptosis.
Hippo pathway mutations in mice and flies give rise to tumours.
Hippo pathway activity seems to be frequently deregulated...

Alternative Titles

Full title

The Hippo pathway and human cancer

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1328515214

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1328515214

Other Identifiers

ISSN

1474-175X

E-ISSN

1474-1768

DOI

10.1038/nrc3458

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