The Hippo pathway and human cancer
The Hippo pathway and human cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Key Points
The Hippo pathway is an evolutionarily conserved regulator of tissue growth.
The Hippo pathway controls multiple cellular functions that are central to tumorigenesis, including proliferation and apoptosis.
Hippo pathway mutations in mice and flies give rise to tumours.
Hippo pathway activity seems to be frequently deregulated...
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Full title
The Hippo pathway and human cancer
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TN_cdi_proquest_miscellaneous_1328515214
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1328515214
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ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc3458