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Rescuing cocaine-induced prefrontal cortex hypoactivity prevents compulsive cocaine seeking

Rescuing cocaine-induced prefrontal cortex hypoactivity prevents compulsive cocaine seeking

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1331088084

Rescuing cocaine-induced prefrontal cortex hypoactivity prevents compulsive cocaine seeking

About this item

Full title

Rescuing cocaine-induced prefrontal cortex hypoactivity prevents compulsive cocaine seeking

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2013-04, Vol.496 (7445), p.359-362

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

A study of compulsive drug-seeking behaviour in rats reveals that prolonged cocaine self-administration decreases prelimbic cortex activity resulting in increased compulsive drug-seeking actions; conversely, increasing activity in the prelimbic cortex decreases drug-seeking behaviour, a finding relevant to addiction treatment.
Prefrontal cortex...

Alternative Titles

Full title

Rescuing cocaine-induced prefrontal cortex hypoactivity prevents compulsive cocaine seeking

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1331088084

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1331088084

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature12024

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