Rescuing cocaine-induced prefrontal cortex hypoactivity prevents compulsive cocaine seeking
Rescuing cocaine-induced prefrontal cortex hypoactivity prevents compulsive cocaine seeking
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
A study of compulsive drug-seeking behaviour in rats reveals that prolonged cocaine self-administration decreases prelimbic cortex activity resulting in increased compulsive drug-seeking actions; conversely, increasing activity in the prelimbic cortex decreases drug-seeking behaviour, a finding relevant to addiction treatment.
Prefrontal cortex...
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Full title
Rescuing cocaine-induced prefrontal cortex hypoactivity prevents compulsive cocaine seeking
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TN_cdi_proquest_miscellaneous_1331088084
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1331088084
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature12024