Adaptive designs for dual-agent phase I dose-escalation studies
Adaptive designs for dual-agent phase I dose-escalation studies
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
With increasing numbers of anticancer drugs requiring testing, new adaptive model-based phase I trial designs can improve on current practice by exploring a wider range of dose combinations than standard phase I methods. In this Review, the authors describe the methods available as well as the opportunities and challenges faced in dual-agent phase...
Alternative Titles
Full title
Adaptive designs for dual-agent phase I dose-escalation studies
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1347259117
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1347259117
Other Identifiers
ISSN
1759-4774,1759-4782
E-ISSN
1759-4782
DOI
10.1038/nrclinonc.2013.35
