Promotion of DNA repair by nuclear IKKβ phosphorylation of ATM in response to genotoxic stimuli
Promotion of DNA repair by nuclear IKKβ phosphorylation of ATM in response to genotoxic stimuli
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Author / Creator
Sakamoto, K , Hikiba, Y , Nakagawa, H , Hirata, Y , Hayakawa, Y , Kinoshita, H , Nakata, W , Sakitani, K , Takahashi, R , Akanuma, M , Kamata, H and Maeda, S
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Ataxia-telangiectasia mutated (ATM) is one of the key molecules involved in the cellular response to DNA damage. A portion of activated ATM is exported from the nucleus into the cytoplasm, where it activates the I kappa B kinase/nuclear factor kappa B (IKK/NF-κB) signaling pathway. It has been thought that activated IKKβ, which is a critical kinase...
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Full title
Promotion of DNA repair by nuclear IKKβ phosphorylation of ATM in response to genotoxic stimuli
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TN_cdi_proquest_miscellaneous_1348484763
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1348484763
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2012.192
