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Coagulation factor X shields adenovirus type 5 from attack by natural antibodies and complement

Coagulation factor X shields adenovirus type 5 from attack by natural antibodies and complement

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1348486219

Coagulation factor X shields adenovirus type 5 from attack by natural antibodies and complement

About this item

Full title

Coagulation factor X shields adenovirus type 5 from attack by natural antibodies and complement

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2013-04, Vol.19 (4), p.452-457

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Understanding how adenoviruses transduce cells is important for their use and development as vaccine vectors. Adenovirus type 5 (Ad5) is known to bind coagulation factor X (FX), and FX is thought to act as a bridge between the virus and its receptor on hepatocytes. Andrew Byrnes and his colleagues now report that the major role of FX binding to Ad5...

Alternative Titles

Full title

Coagulation factor X shields adenovirus type 5 from attack by natural antibodies and complement

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1348486219

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1348486219

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm.3107

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