FHL1 on chromosome X is a single-hit gastrointestinal tumor-suppressor gene and contributes to the f...
FHL1 on chromosome X is a single-hit gastrointestinal tumor-suppressor gene and contributes to the formation of an epigenetic field defect
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Author / Creator
Asada, K , Ando, T , Niwa, T , Nanjo, S , Watanabe, N , Okochi-Takada, E , Yoshida, T , Miyamoto, K , Enomoto, S , Ichinose, M , Tsukamoto, T , Ito, S , Tatematsu, M , Sugiyama, T and Ushijima, T
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Tumor-suppressor genes on chromosome X can be inactivated by a single hit, any of the point mutations, chromosomal loss and aberrant DNA methylation. As aberrant DNA methylation can be induced frequently, we here aimed to identify a tumor-suppressor gene on chromosome X inactivated by promoter DNA methylation. Of 69 genes on chromosome X upregulate...
Alternative Titles
Full title
FHL1 on chromosome X is a single-hit gastrointestinal tumor-suppressor gene and contributes to the formation of an epigenetic field defect
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Record Identifier
TN_cdi_proquest_miscellaneous_1352288903
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1352288903
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2012.228
