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A clinically significant interaction between warfarin and simvastatin is unique to carriers of the C...

A clinically significant interaction between warfarin and simvastatin is unique to carriers of the C...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1356930996

A clinically significant interaction between warfarin and simvastatin is unique to carriers of the CYP2C93 allele

About this item

Full title

A clinically significant interaction between warfarin and simvastatin is unique to carriers of the CYP2C93 allele

Publisher

England: Future Medicine Ltd

Journal title

Pharmacogenomics, 2012-05, Vol.13 (7), p.757-762

Language

English

Formats

Publication information

Publisher

England: Future Medicine Ltd

More information

Scope and Contents

Contents

Simvastatin interacts with warfarin, but the strength of the interaction varies between individual patients, indicating a genetic predisposition.
The influence of the CYP2C9*2 and CYP2C9*3 polymorphisms on the interaction between simvastatin and warfarin was analyzed in data from 1132 patients.
Simvastatin use reduced warfarin dose requiremen...

Alternative Titles

Full title

A clinically significant interaction between warfarin and simvastatin is unique to carriers of the CYP2C93 allele

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1356930996

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1356930996

Other Identifiers

ISSN

1462-2416

E-ISSN

1744-8042

DOI

10.2217/pgs.12.40

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