Cyst expansion and regression in a mouse model of polycystic kidney disease
Cyst expansion and regression in a mouse model of polycystic kidney disease
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Publisher
United States: Elsevier Inc
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Language
English
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Publisher
United States: Elsevier Inc
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Contents
Autosomal-dominant polycystic kidney disease is characterized by progressive cyst formation and fibrosis in the kidneys. Here we describe an orthologous Pkd1nl,nl mouse model, with reduced expression of the normal Pkd1 transcript, on a fixed genetic background of equal parts C57Bl/6 and 129Ola/Hsd mice (B6Ola-Pkd1nl,nl). In these mice, the first cy...
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Full title
Cyst expansion and regression in a mouse model of polycystic kidney disease
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TN_cdi_proquest_miscellaneous_1364709806
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1364709806
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ISSN
0085-2538
E-ISSN
1523-1755
DOI
10.1038/ki.2013.13
