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Rapid Detection of SNP (c.309T>G) in the MDM2 Gene by the Duplex SmartAmp Method. e60151

Rapid Detection of SNP (c.309T>G) in the MDM2 Gene by the Duplex SmartAmp Method. e60151

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1367492860

Rapid Detection of SNP (c.309T>G) in the MDM2 Gene by the Duplex SmartAmp Method. e60151

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Full title

Rapid Detection of SNP (c.309T>G) in the MDM2 Gene by the Duplex SmartAmp Method. e60151

Journal title

PloS one, 2013-04, Vol.8 (4)

Language

English

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Contents

Background Genetic polymorphisms in the human MDM2 gene are suggested to be a tumor susceptibility marker and a prognostic factor for cancer. It has been reported that a single nucleotide polymorphism (SNP) c.309T>G in the MDM2 gene attenuates the tumor suppressor activity of p53 and accelerates tumor formation in humans. Methodology In this study,...

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Full title

Rapid Detection of SNP (c.309T>G) in the MDM2 Gene by the Duplex SmartAmp Method. e60151

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TN_cdi_proquest_miscellaneous_1367492860

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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1367492860

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E-ISSN

1932-6203

DOI

10.1371/journal.pone.0060151

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