Allosteric inhibition through suppression of transient conformational states
Allosteric inhibition through suppression of transient conformational states
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Advanced NMR studies of catabolite activator protein show that allosteric inhibitors can prevent conformational changes needed for a protein to bind its ligand, offering an explanation for why these inhibitors may not appear to cause any effect when monitored using static techniques.
The ability to inhibit binding or enzymatic activity is key to...
Alternative Titles
Full title
Allosteric inhibition through suppression of transient conformational states
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TN_cdi_proquest_miscellaneous_1369716518
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1369716518
Other Identifiers
ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/nchembio.1250
