Kindlin-1 regulates mitotic spindle formation by interacting with integrins and Plk-1
Kindlin-1 regulates mitotic spindle formation by interacting with integrins and Plk-1
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Kindlin-1 binds to integrins and regulates integrin activation at cell adhesions. Here we report a new function of Kindlin-1 in regulating spindle assembly. We show that Kindlin-1 localizes to centrosomes, its concentration peaking during G2/M, where it associates with various pericentriolar material proteins, including Polo-like kinase 1. Short in...
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Kindlin-1 regulates mitotic spindle formation by interacting with integrins and Plk-1
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TN_cdi_proquest_miscellaneous_1372698047
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1372698047
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms3056
