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ADAM17 mediates hypoxia-induced drug resistance in hepatocellular carcinoma cells through activation...

ADAM17 mediates hypoxia-induced drug resistance in hepatocellular carcinoma cells through activation...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1373443471

ADAM17 mediates hypoxia-induced drug resistance in hepatocellular carcinoma cells through activation of EGFR/PI3K/Akt pathway

About this item

Full title

ADAM17 mediates hypoxia-induced drug resistance in hepatocellular carcinoma cells through activation of EGFR/PI3K/Akt pathway

Publisher

Boston: Springer US

Journal title

Molecular and cellular biochemistry, 2013-08, Vol.380 (1-2), p.57-66

Language

English

Formats

Publication information

Publisher

Boston: Springer US

More information

Scope and Contents

Contents

A disintegrin and metalloproteinase-17 (ADAM17) is a member of the metalloproteinase superfamily and involved in the cleavage of ectodomain of many transmembrane proteins. ADAM17 is overexpressed in a variety of human tumors, which is associated with tumor development and progression. In the present study, we sought to investigate the expression an...

Alternative Titles

Full title

ADAM17 mediates hypoxia-induced drug resistance in hepatocellular carcinoma cells through activation of EGFR/PI3K/Akt pathway

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1373443471

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1373443471

Other Identifiers

ISSN

0300-8177

E-ISSN

1573-4919

DOI

10.1007/s11010-013-1657-z

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