Mast cell tryptase reduces junctional adhesion molecule-A (JAM-A) expression in intestinal epithelia...
Mast cell tryptase reduces junctional adhesion molecule-A (JAM-A) expression in intestinal epithelial cells: implications for the mechanisms of barrier dysfunction in irritable bowel syndrome
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Full title
Author / Creator
Publisher
United States: Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins
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Language
English
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Publisher
United States: Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins
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Scope and Contents
Contents
The objective of this study was to investigate how mast cell tryptase may influence intestinal permeability and tight junction (TJ) proteins in vitro and explore translation to irritable bowel syndrome (IBS).
We investigated the effect of: (1) tryptase on Caco-2 monolayers, (2) mast cell degranulation in a Caco-2/human mast cell-1 (HMC-1) co-cul...
Alternative Titles
Full title
Mast cell tryptase reduces junctional adhesion molecule-A (JAM-A) expression in intestinal epithelial cells: implications for the mechanisms of barrier dysfunction in irritable bowel syndrome
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_proquest_miscellaneous_1393821582
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1393821582
Other Identifiers
ISSN
0002-9270
E-ISSN
1572-0241
DOI
10.1038/ajg.2013.92
