FGF21 Can Be Mimicked In Vitro and In Vivo by a Novel Anti-FGFR1c/ beta -Klotho Bispecific Protein....
FGF21 Can Be Mimicked In Vitro and In Vivo by a Novel Anti-FGFR1c/ beta -Klotho Bispecific Protein. e61432
About this item
Full title
FGF21 Can Be Mimicked In Vitro and In Vivo by a Novel Anti-FGFR1c/ beta -Klotho Bispecific Protein. e61432
Author / Creator
Journal title
PloS one, 2013-04, Vol.8 (4)
Language
English
Formats
Subjects
More information
Scope and Contents
Contents
The endocrine hormone FGF21 has attracted considerable interest as a potential therapeutic for treating diabetes and obesity. As an alternative to the native cytokine, we generated bispecific Avimer polypeptides that bind with high affinity and specificity to one of the receptor and coreceptor pairs used by FGF21, FGFR1c and beta -Klotho. These Avi...
Alternative Titles
Full title
FGF21 Can Be Mimicked In Vitro and In Vivo by a Novel Anti-FGFR1c/ beta -Klotho Bispecific Protein. e61432
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1399917545
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1399917545
Other Identifiers
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0061432
How to access this item
Log in as a Library member
