The ATM protein kinase: regulating the cellular response to genotoxic stress, and more
The ATM protein kinase: regulating the cellular response to genotoxic stress, and more
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Key Points
ATM is a powerful protein kinase, the function of which is lost in patients with the genomic instability syndrome ataxia-telangiectasia.
The most documented function of ATM is mobilizing and regulating the cellular response to DNA double-strand breaks (DSBs).
ATM is a member of the PIKK (PI3K-like protein kinase) family and has...
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Full title
The ATM protein kinase: regulating the cellular response to genotoxic stress, and more
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TN_cdi_proquest_miscellaneous_1399932056
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1399932056
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ISSN
1471-0072
E-ISSN
1471-0080
DOI
10.1038/nrm3546