Chimeric 5/35 adenovirus-mediated Dickkopf-1 overexpression suppressed tumorigenicity of CD44+ gastr...
Chimeric 5/35 adenovirus-mediated Dickkopf-1 overexpression suppressed tumorigenicity of CD44+ gastric cancer cells via attenuating Wnt signaling
About this item
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Author / Creator
Wang, Bin , Liu, Jia , Ma, Lei Na , Xiao, Hua Liang , Wang, Ya Zhou , Li, Yan , Wang, Zhe , Fan, Linli , Lan, Chunhui , Yang, Min , Hu, Lu , Wei, Yanlin , Bian, Xiu Wu , Chen, Dongfeng and Wang, Jun
Publisher
Tokyo: Springer Japan
Journal title
Language
English
Formats
Publication information
Publisher
Tokyo: Springer Japan
Subjects
More information
Scope and Contents
Contents
Background
Gastric cancer stem cells (CSCs), which require activation of Wnt signaling to maintain their self-renewal and tumorigenicity, are proposed to be critical targets for effective therapy of gastric carcinomas. Gene therapies that are delivered by adenovirus of serotype 5 (Ad5) or chimeric 5/35(Ad5/35) adenovirus have shown promise for t...
Alternative Titles
Full title
Chimeric 5/35 adenovirus-mediated Dickkopf-1 overexpression suppressed tumorigenicity of CD44+ gastric cancer cells via attenuating Wnt signaling
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1406175497
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1406175497
Other Identifiers
ISSN
0944-1174
E-ISSN
1435-5922
DOI
10.1007/s00535-012-0711-z
