Antagonism of the histamine H sub(4) receptor reduces LPS-induced TNF production in vivo
Antagonism of the histamine H sub(4) receptor reduces LPS-induced TNF production in vivo
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English
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Objective: Antagonism of the histamine H sub(4) receptor (H sub(4)R) has been shown to be anti-inflammatory in a number of preclinical disease models, however the exact mechanisms behind this are still being uncovered. In vitro, the receptor interacts with TLR and impacts inflammatory mediator production from a number of different cell types. Here...
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Antagonism of the histamine H sub(4) receptor reduces LPS-induced TNF production in vivo
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TN_cdi_proquest_miscellaneous_1412500478
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1412500478
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ISSN
1023-3830
E-ISSN
1420-908X
DOI
10.1007/s00011-013-0612-5