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A Robust Method to Analyze Copy Number Alterations of Less than 100 kb in Single Cells Using Oligonu...

A Robust Method to Analyze Copy Number Alterations of Less than 100 kb in Single Cells Using Oligonu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1412501061

A Robust Method to Analyze Copy Number Alterations of Less than 100 kb in Single Cells Using Oligonucleotide Array CGH. e67031

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Full title

A Robust Method to Analyze Copy Number Alterations of Less than 100 kb in Single Cells Using Oligonucleotide Array CGH. e67031

Journal title

PloS one, 2013-06, Vol.8 (6)

Language

English

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Contents

Comprehensive genome wide analyses of single cells became increasingly important in cancer research, but remain to be a technically challenging task. Here, we provide a protocol for array comparative genomic hybridization (aCGH) of single cells. The protocol is based on an established adapter-linker PCR (WGAM) and allowed us to detect copy number a...

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Full title

A Robust Method to Analyze Copy Number Alterations of Less than 100 kb in Single Cells Using Oligonucleotide Array CGH. e67031

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TN_cdi_proquest_miscellaneous_1412501061

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1412501061

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E-ISSN

1932-6203

DOI

10.1371/journal.pone.0067031

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