Assessment of SLX4 Mutations in Hereditary Breast Cancers. e66961
Assessment of SLX4 Mutations in Hereditary Breast Cancers. e66961
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Full title
Assessment of SLX4 Mutations in Hereditary Breast Cancers. e66961
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Journal title
PloS one, 2013-06, Vol.8 (6)
Language
English
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Contents
Background SLX4 encodes a DNA repair protein that regulates three structure-specific endonucleases and is necessary for resistance to DNA crosslinking agents, topoisomerase I and poly (ADP-ribose) polymerase (PARP) inhibitors. Recent studies have reported mutations in SLX4 in a new subtype of Fanconi anemia (FA), FA-P. Monoallelic defects in severa...
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Full title
Assessment of SLX4 Mutations in Hereditary Breast Cancers. e66961
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TN_cdi_proquest_miscellaneous_1412551963
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1412551963
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E-ISSN
1932-6203
DOI
10.1371/journal.pone.0066961
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