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Mixed-effects beta regression for modeling continuous bounded outcome scores using NONMEM when data...

Mixed-effects beta regression for modeling continuous bounded outcome scores using NONMEM when data...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1413162237

Mixed-effects beta regression for modeling continuous bounded outcome scores using NONMEM when data are not on the boundaries

About this item

Full title

Mixed-effects beta regression for modeling continuous bounded outcome scores using NONMEM when data are not on the boundaries

Publisher

Boston: Springer US

Journal title

Journal of pharmacokinetics and pharmacodynamics, 2013-08, Vol.40 (4), p.537-544

Language

English

Formats

Publication information

Publisher

Boston: Springer US

More information

Scope and Contents

Contents

Beta regression models have been recommended for continuous bounded outcome scores that are often collected in clinical studies. Implementing beta regression in NONMEM presents difficulties since it does not provide gamma functions required by the beta distribution density function. The objective of the study was to implement mixed-effects beta reg...

Alternative Titles

Full title

Mixed-effects beta regression for modeling continuous bounded outcome scores using NONMEM when data are not on the boundaries

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1413162237

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1413162237

Other Identifiers

ISSN

1567-567X

E-ISSN

1573-8744

DOI

10.1007/s10928-013-9318-0

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